1. Gustavo Vasen, Paula Dunayevich and Alejandro Colman-Lerner. (2020) Mitotic and pheromone-specific intrinsic polarization cues interfere with gradient sensing in Saccharomyces cerevisiae. Proc.Natl.Acad.Sci.U.S.A, epub Mar 9 doi.org/10.1073/pnas.1912505117
2. Juan Pablo Di Bella, Alejandro Colman-Lerner*, Alejandra Ventura*. (2018) Properties of cell signaling pathways and gene expression systems operating far from steady-state. Scientific Reports Vol 8, Issue 1, e17035. doi.org/10.1038/s41598-018-34766-0. *: co-corresponding authors.
3. Paula Dunayevich*, Rodrigo Baltanás*, José Clemente, Alicia Couto, Daiana Sapochnik,Gustavo Vasen and Alejandro Colman-Lerner. (2018) Heat-stress triggers MAPK crosstalk to turn on the hyper-osmotic response pathway. Scientific Reports Vol 8, Issue 1, e15168. doi.org/10.1038/s41598-018-33203-6. *: equally contributing authors.
4. C. Gustavo Pesce, Stefan Zdraljevic, William J. Peria, Alan Bush, María Victoria Repetto, Daniel Rockwell, Richard Yu, Alejandro Colman-Lerner*and Roger Brent*. (2018) Single-cell profiling screen identifies microtubule-dependent reduction of variability in cell signaling. Molecular Systems Biology 14(4):e7390. doi.org/10.15252/msb.20167390. *: co-corresponding authors.
5. María Victoria Repetto, Matthew J. Winters, Alan Bush, Wolfgang Reiter, David Maria Hollenstein, Gustav Ammerer, Peter M. Pryciak*, and Alejandro Colman-Lerner*. (2018) CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5. Molecular Cell Vol 69, Issue 6, 15 March 2018, Pages 938–952.e6. doi.org/10.1016/j.molcel.2018.02.018. *: co-corresponding authors.
6. Edgar Altszyler, Alejandra C. Ventura, Alejandro Colman-Lerner, and Ariel Chernomoretz. (2017). Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations. Plos One 12(6):e0180083. doi.org/10.1371/journal.pone.0180083.
7. Alan Bush*, Gustavo Vasen*, Andreas Constantinou#, Paula Dunayevich#, Inés Patop, Matías Blaustein, and Alejandro Colman-Lerner. (2016) Yeast GPCR signaling reflects the fraction of occupied receptors, not the number. Molecular Systems Biology12(12):898. doi.org/10.15252/msb.20166910. * o #: equally contributing authors.
8. Steven S. Andrews, William J. Peria, Richard C. Yu,
Alejandro Colman-Lerner, Roger Brent. (2016) Push-Pull and Feedback Mechanisms Can Align Signaling System Outputs with Inputs. Cell Systems 3, 1-12dx. doi.org/10/2016/j.cels.2016.10.002.
9. Markus Karlsson, David L.I. Janzén, Lucia Durrieu, Alejandro Colman-Lerner, Maria C. Kjellsson and Gunnar Cedersund. (2015)Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use it. BMC Systems Biology 9:52 1-15. doi.org/10.1186/s12918-015-0203-x
10. Andreas Doncic, Oguzhan Atay, Ervin Valk, Alicia Grande, Alan Bush, Gustavo Vasen, Alejandro Colman-Lerner, Mart Loog, and Jan M. Skotheim. (2015) Compartmentalization of a Bistable Switch Enables Memory to Cross a Feedback-Driven Transition. Cell 160, 1182–1195. doi.org/10.1016/j.cell.2015.02.032
11. Altszyler, E; Ventura, A; Colman-Lerner, A; and Chernomoretz, A. (2014) Impact of upstream and downstream constraints on a signaling module’s ultrasensitivity. Phys. Biol. 11 066003. doi.org/10.1088/1478-3975/11/6/066003
12. Ventura, A. C. Bush, A. Vasen, G. Goldin, M. Burkinshaw, B. Bhattacharjee, Nirveek, Folch, A. Brent, R. Chernomoretz, A and Colman-Lerner, A. (2014) Utilization of extracellular information before equilibrium receptor binding expands and shifts the input dynamic range. Proc.Natl.Acad.Sci.U.S.A, Sep 16;111(37):E3860-9. Epub Aug 29. doi: 10.1073/pnas.1322761111.
13. Sigaut L, Pearson JE, Colman-Lerner A, and Ponce Dawson S (2014). Messages do diffuse faster than messengers: reconciling disparate estimates of the morphogen bicoid diffusion coefficient. PLoS Comput Biol 10(6):e1003629. doi.org/10.1371/journal.pcbi.1003629.
14. Guillermo Risso, Federico Pelish, Berta Pozzi, Pablo Mammi, Matías Blaustein, Alejandro Colman-Lerner, and Anabella Srebrow. (2013) Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle. Cell Cycle, 12:19. doi.org/10.4161/cc.26183
15. Matías Blaustein, Daniela Pérez-Munizaga, Manuel Alejandro Sánchez, Carolina Urrutia, Alicia Grande, Guillermo Risso, Anabella Srebrow, Jennifer Alfaro and Alejandro Colman-Lerner. (2013) Modulation of the Akt Pathway Reveals a Novel Link with PERK/eIF2alpha, which Is Relevant During Hypoxia. PlosONE, Jul 29;8(7):e69668. doi.org/10.1371/journal.pone.0069668
16. Rodrigo Baltanás, Alan Bush, Alicia Couto, Lucía Durrieu, Stefan Hohmann, and Alejandro Colman-Lerner. (2013). Pheromone-induced morphogenesis improves osmoadaptation capacity by activating the HOG MAPK pathway. Science Signaling, Apr 23;6(272):ra26. doi: 10.1126/scisignal.2003312. doi.org/10.1126/scisignal.2003312
17. Alan Bush and Alejandro Colman-Lerner. (2013) Quantitative measurement of protein relocalization in live cells. Biophysical Journal 104:727. doi.org/10.1016/j.bpj.2012.12.030
18. Jörg Schaber, Rodrigo Baltanas, Alan Bush, Edda Klipp, and Alejandro Colman- Lerner. (2012) Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast. Molecular Systems Biology 8:622.doi.org/10.1038/msb2012.53.
19. Alan Bush, Ariel Chernomoretz,Richard Yu, Andrew Gordon, and Alejandro Colman-Lerner. (2012). Using Cell-ID 1.4 with R for Microscope-Based Cytometry. Current protocols in molecular biology, capítulo 14, unidad 14.18. doi.org/10.1002/0471142727.mb1418s100.
20. Marina Riggio, María Laura Polo, Matías Blaustein, Alejandro Colman-Lerner, Isabel Lüthy, Claudia Lanari and Virginia Novaro. (2012). PI3K/AKT pathway regulates ligand-independent activation of steroid receptors, hormone independence and tumor differentiation in breast cancer. Carcinogenesis, 33(3):509-18. doi.org/10.1093/carcin/bgr303.
21. Ty M. Thomson, Ty M, Benjamin, Kirsten R., Bush, Alan , Love, Tonya, Pincus, David, Resnekov, Orna, Yu, Richard C., Gordon, Andrew, Colman- Lerner, Alejandro, Endy, Drew, and Brent, Roger. (2011). Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range. Proc.Natl.Acad.Sci.U.S.A, 108(50):20265-70. doi.org/10.1073/pnas.1004042108
22. Bodenmiller, Bernd; Wanka, Stefanie; Kraft, Claudine; Urban, Jörg; Campbell, David; Pedrioli, Patrick; Gerrits, Bertran; Picotti, Paola; Lam, Henry; Vitek, Olga; Brusniak, Mi-Youn; Roschitzki, Bernd; Zhang, Chao; Schlapbach, Ralph; Shokat, Kevan; Colman-Lerner, Alejandro; Nesvizhskii, Alexey; Peter, Matthias; Loewith, Robbie; von Mering,Christian, and Aebersold, Ruedi.(2010). Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast. Science Signaling 3, 153. doi.org/10.1126/scisignal.2001182.
23. Sigaut, L., Ponce, M.L., Colman-Lerner, A., and Ponce Dawson, S. (2010). Optical techniques provide information on various effective diffusion coefficients in the presence of traps. Physical Review E 82(5), 051912. doi.org/10.1103/PhysRevE.82.051912.
24. Yu, R. C., Pesce, C. G., Colman-Lerner, A., Lok, L., Pincus, D., Serra, E., Holl, M., Benjamin, K., Gordon, A. and Brent, R. (2008). Negative feedback that improves information transmission in yeast signalling. Nature 465, 755-761. doi.org/0.1038/nature07513.
25. Yu, R.C., Resnekov, O., Abola, P., Andrews, A., Benjamin, K., Bruck, J., Burbulis, I., Colman-Lerner, A., Endy, D., Gordon, A., Holl, M., Lok, L., Maxwell, R., Pesce, C.G., Serra, E., Smith, R.D., Thomson, T., Tsong, A., and Brent, R. (2008). The Alpha Project, a model system for systems biology research. IET Systems Biology, 2, 222-233. doi.org/10.1049/iet-syb:20080127.
26. Chernomoretz, A., Bush, A., Yu, R., Gordon, A., and Colman-Lerner, A. (2008). Using Cell-ID-1.4 with R for microscope-based cytometry.Current protocols in molecular biology. Capítulo 14, unidad 18. Edited by Frederick M. Ausubel et al. doi.org/10.1002/0471142727.mb1418s84.
27. Gordon, A.*, Colman-Lerner, A*#., Chin, T.E., Benjamin, K.R., Yu, R.C., and Brent, R. (2007). Single-cell quantification of molecules and rates using open-source microscope-based cytometry. Nat Methods 4, 175-181. *: equally contributing authors. #: corresponding author. doi.org/10.1038/nmeth1008.
28. Fazzini, M., Vallejo, G., Colman-Lerner, A., Trigo, R., Campo, S., Baranao, J. L. & Saragueta, P. (2006). Transforming growth factor-b1 regulates follistatin mRNA expression during in vitro bovine granulosa cell differentiation. J Cell Physiol 207(1): 40-48. doi.org/10.1002/jcp.20533
29. Colman-Lerner, A.*#, Gordon, A.*#, Serra, E., Chin, T., Resnekov, O., Endy, D., Pesce, C.G., and Brent, R#. (2005). Regulated cell-to-cell variation in a cell-fate decision system. Nature 437, 699-706. *: equally contributing authors. # corresponding authors).doi.org/10.1038/nature03998 .
30. Novaro, V., Pustovrh, C., Colman-Lerner, A., Radisky, D., Lo Nostro, F., Paz, D., Jawerbaum, A. and Gonzalez, E. (2002). “Nitric oxide induces gelatinase A (matrix metalloproteinase 2) during rat embryo implantation.” Fertility and Sterility 78(6): 1278-87. doi.org/10.1016/s0015-0282(02)04240-1
31. Chiappe, M. E., Lattanzi, M. L., Colman-Lerner, A. A., Baranao, J. L. and Saragueta, P. (2002). “Expression of 3 beta-hydroxysteroid dehydrogenase in early bovine embryo development.” Molecular Reproduction and Development 61(2): 135-41. doi.org/10.1002/mrd.1140
32. Novaro, V., Colman-Lerner, A., Ortega, F. V., Jawerbaum, A., Paz, D., Lo Nostro, F., Pustovrh, C., Gimeno, M. F. and Gonzalez, E. (2001). “Regulation of metalloproteinases by nitric oxide in human trophoblast cells in culture.” Reprodroduction Fertility and Development 13(5-6): 411-20. doi.org/10.1071/rd01036
33. Colman-Lerner, A.*, Chin, T.E., and Brent, R. (2001). Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates. Cell 107, 739-750. doi.org/10.1016/s0092-8674(01)00596-7. * corresponding author.
34. Colman-Lerner, A., and Brent, R. (2000). Using Peptide Aptamers to Analyse the Proteome. New Technologies for Life Sciences: A Trends Guide Special Issue, 56-60.
35. Pomata, P. E., Colman-Lerner, A. A., Baranao, J. L. and Fiszman, M. L. (2000). “In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta.” Brain Research, Developmental Brain Research 120(1): 83-6. doi.org/0.1016/s0165-3806(99)00181-9
36. Geyer, C.R., Colman-Lerner, A*., and Brent, R. (1999). “Mutagenesis” by peptide aptamers identifies genetic network members and pathway connections. Proc.Natl.Acad.Sci.U.S.A 96, 8567-8572. *: corresponding author”. doi.org/10.1073/pnas.96.15.8567.
37. Colman-Lerner, A., Fischman, M.L., Lanuza, G.M., Bissell, D.M., Kornblihtt, A.R., and Baranao, J.L. (1999). Evidence for a role of the alternatively spliced ED-I sequence of fibronectin during ovarian follicular development. Endocrinology 140, 2541-2548. doi.org/10.1210/en.140.6.2541
38. Pignataro, L., Lerner, A. A., Baranao, J. L. and de Plazas, S. F. (1998). “Biosynthesis of progesterone derived neurosteroids by developing avian CNS: in vitro effects on the GABAA receptor complex.” International Journal of Developmental Neuroscience 16(5): 433-41. doi.org/10.1016/s0736-5748(98)00015-x
39. Colman-Lerner, A. A., Fischman, M. L., Lanuza, G., Cramer, P., Kornblihtt, A. and Baranao, J. L. (1997). “[Role of different forms of fibronectin in vitro bovine follicular development].” Medicina (B Aires) 57(3): 332-6. pmid: 9640769
40. Colman-Lerner, A. A., Salamone, D. F., Chiappe, M. E. and Baranao, J. L. (1995). “Comparative studies between freshly isolated and spontaneously immortalized bovine granulosa cells: protein secretion, steroid metabolism, and responsiveness to growth factors.” Journal of Cellular Physiology 164(2): 395-403. doi.org/10.1002/jcp.1041640220
