CV
Dr. Alejandro Colman-Lerner
Profesor Adjunto, Departamento de Fisiología, Biología Molecular y Celular, FCEN, UBA.
Investigador Principal CONICET
Datos académicos
Título/s: Doctor de la Universidad de Buenos Aires
Licenciado en Ciencias Biológicas
Categoría: INV PRINCIPAL
Disciplina científica: Biología
Disciplina desagregada: BIOLOGIA-CELULAR Y MOLECULAR
Campo de aplicación: Prom.Gral.del Conoc.-Cs.Exactas y Naturales
Salud humana
Salud humana
Especialidad: Transducción de señales, biología de sistemas, expresión asimétrica
Tema: Sistemas moleculares que gobiernan la expresión génica asimétrica y la transducción y procesamiento de señales en Saccharomyces cerevisiae y en células epiteliales de mama y su efecto sobre la toma de decisiones que afectan el destino celular.
Tema en inglés: MOLECULAR SYSTEMS THAT GOVERN ASYMMETRIC GENE EXPRESSION AND SIGNAL TRANSDUCTION AND PROCESSING IN SACCHAROMYCES CEREVISIAE AND IN MAMMARY EPITHELIAL CELLS AND THEIR EFFECT ON CELL FATE DECISIONS
Palabras clave: DIFERENCIACION // LEVADURA // SEÑALIZACION
Palabras clave en inglés: DIFFERENTIATION // YEAST // SIGNALING
Lugar de trabajo: [IFIBYNE] INSTITUTO DE FISIOLOGIA, BIOLOGIA MOLECULAR Y NEUROCIENCIAS –
[OCA – CDAD. UNIVERSITARIA] OFICINA DE COORDINACION ADMINISTRATIVA CIUDAD UNIVERSITARIA –
[CONICET] CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS –
Director de:
BECARIOS
Co director de :
BECARIOS
Artículos
VASEN, GUSTAVO; DUNAYEVICH, PAULA; COLMAN-LERNER, ALEJANDRO.
Mitotic and pheromone-specific intrinsic polarization cues interfere with gradient sensing in Saccharomyces cerevisiae.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2020
DI-BELLA, JUAN PABLO; COLMAN-LERNER, ALEJANDRO; VENTURA, ALEJANDRA C.
Properties of cell signaling pathways and gene expression systems operating far from steady-state
Scientific Reports; Año: 2018 vol. 8
VICTORIA REPETTO; MATTHEW WINTERS; ALAN BUSH; WOLFGANG REITER; DAVID MARIA HOLLENSTEIN; GUSTAV AMMERER; PETER PRYCIAK; ALEJANDRO COLMAN LERNER
CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5
MOLECULAR CELL; Lugar: United States; Año: 2018 vol. 69
GUSTAVO PESCE; STEFAN ZDRALJEVIC; WILLIAM PERIA; ALAN BUSH; VICTORIA REPETTO; DAN ROCKWELL; RICHARD YU; ALEJANDRO COLMAN LERNER; ROGER BRENT
Single-cell profiling screen identifies microtubule-dependent reduction of variability in cell signaling
MOLECULAR SYSTEMS BIOLOGY; Lugar: Londres; Año: 2018 vol. 14 p. 1 – 20
PAULA DUNAYEVICH; RODRIGO BALTANÁS; JOSÉ CLEMENTE; ALICIA COUTO; DAIANA SAPOCHNIK; GUSTAVO VASEN; ALEJANDRO COLMAN LERNER
Heat-stress triggers MAPK crosstalk to turn on the hyper-osmotic response pathway
Scientific Reports; Año: 2018
EDGAR ALTSZYLER; ALEJANDRA VENTURA; ALEJANDRO COLMAN-LERNER; ARIEL CHERNOMORETZ
Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations
PLOS ONE; Lugar: San Francisco; Año: 2017
STEVE ANDREWS; WILLIAM PERIA; RICHARD YU; ALEJANDRO COLMAN LERNER; ROGER BRENT
Push-pull and feedback mechanisms can align signaling system outputs with inputs
Cell Systems; Año: 2016 vol. 3 p. 1 – 12
ALAN BUSH; GUSTAVO VASEN; ANDREAS CONSTANTINOU; PAULA DUNAYEVICH; INÉS PATOP; MATÍAS BLAUSTEIN; ALEJANDRO COLMAN LERNER
Yeast GPCR signaling reflects the fraction of occupied receptors, not the number
MOLECULAR SYSTEMS BIOLOGY; Lugar: Heidelberg; Año: 2016 vol. 12 p. 1 – 20
ANDREAS DONCIC; OGUZHAN ATAY; ERVIN VALK; ALICIA GRANDE; ALAN BUSH; GUSTAVO VASEN; ALEJANDRO COLMAN LERNER; MART LOOG; JAN SKOTHEIM
Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition
CELL; Lugar: United States; Año: 2015 vol. 120
MARCUS KARLSSON; DAVID JANSEN; LUCÍA DURRIEU; ALEJANDRO COLMAN LERNER; MARIA KJELLSSON; GUNNAR CEDERSUND
Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use it
BMC SYSTEMS BIOLOGY; Lugar: Londres; Año: 2015 vol. 9 p. 1 – 15
EDGAR ALTSZYLER; ALEJANDRA VENTURA; ALEJANDRO COLMAN LERNER; ARIEL CHERNOMORETZ
Impact of upstream and downstream constraints on a signaling module’s ultrasensitivity
PHYSICAL BIOLOGY; Lugar: Londres; Año: 2014 vol. 11
LORENA SIGAUT; JOHN PEARSON; ALEJANDRO COLMAN LERNER; SILVINA PONCE DAWSON
Messages Do Diffuse Faster Than Messengers: Reconciling disparate estimates of the morphogen Bicoid diffusion coefficient
PLOS COMPUTATIONAL BIOLOGY; Lugar: San Francisco; Año: 2014 p. 1 – 15
ALEJANDRA VENTURA; ALAN BUSH; GUSTAVO VASEN; MATÍAS GOLDÍN; BRIANNE BURKINSHAW; NIRVEEK BHATTACHARJEE; ALBERT FOLCH; ROGER BRENT; ARIEL CHERNOMORETZ; ALEJANDRO COLMAN LERNER
Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2014
ALAN BUSH; ALEJANDRO COLMAN LERNER
Quantitative Measurement of Protein Relocalization in Live Cells
BIOPHYSICAL JOURNAL; Lugar: United States; Año: 2013 vol. 104 p. 727 – 736
RODRIGO BALTANÁS; ALAN BUSH; ALICIA COUTO ; LUCIA DURRIEU; STEFAN HOHMANN; ALEJANDRO COLMAN LERNER
Pheromone-Induced Morphogenesis Improves Osmoadaptation Capacity by Activating the HOG MAPK Pathway
SCIENCE SIGNALING; Año: 2013 vol. 6 p. 1 – 14
MATÍAS BLAUSTEIN; DANIELA PÉREZ-MUNIZAGA; MANUEL ALEJANDRO SÁNCHEZ; CAROLINA URRUTIA; ALICIA GRANDE; GUILLERMO RISSO; ANABELLA SREBROW; JENNIFER ALFARO; ALEJANDRO COLMAN LERNER
Modulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxia
PLOS ONE; Lugar: San Francisco; Año: 2013 p. 1 – 14
GUILLERMO RISSO; FEDERICO PELISCH; BERTA POZZI; PABLO MAMMI; MATÍAS BLAUSTEIN; ALEJANDRO COLMAN LERNER; ANABELLA SREBROW
Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle
CELL CYCLE; Lugar: Austin, Texas; Año: 2013 vol. 12 p. 1 – 12
ALAN BUSH; ARIEL CHERNOMORETZ; RICHARD YU; ANDREW GORDON; ALEJANDRO COLMAN LERNER
Using Cell-ID 1.4 with R for Microscope-Based Cytometry
Current Protocols in Molecular Biology; Año: 2012 p. 1 – 26
JÖRG SCHABER; RODRIGO BALTANÁS; ALAN BUSH; EDDA KLIPP; ALEJANDRO COLMAN LERNER
Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast
MOLECULAR SYSTEMS BIOLOGY; Lugar: Londres; Año: 2012 p. 1 – 17
MARIANA RIGGIO; MARÍA LAURA POLO; MATÍAS BLAUSTEIN; ALEJANDRO COLMAN LERNER; ISABEL LÜTHY; CLAUDIA LANARI; VIRGINIA NOVARO
PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer
CARCINOGENESIS; Lugar: Oxford; Año: 2011 p. 1 – 10
TY THOMSON; KIRSTEN BENJAMIN; ALAN BUSH; TONYA LOVE; DAVID PINCUS; ORNA RESNEKOV; RICHARD YU; ANDREW GORDON; ALEJANDRO COLMAN LERNER; DREW ENDY; ROGER BRENT
Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2011
BERND BODENMILLER; STEFANIE WANKA; CLAUDINE KRAFT; JÖRG URBAN; DAVID CAMPBELL; PATRICK PEDRIOLI; BERTRAN GERRITS; PAOLA PICOTTI; HENRY LAM; OLGA VITEK; MI-YOUN BRUSNIAK; BERND ROSCHITZKI; CHAO ZHANG; RALPH SCHLAPBACH; KEVAN SHOKAT; ALEJANDRO COLMAN-LERNER; ALEXEY I. NESVIZHSKII; MATTHIAS PETER; ROBBIE LOEWITH; CHRISTIAN VON MERING; RUEDI AEBERSOLD
Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast
SCIENCE SIGNALING; Año: 2010
LORENA SIGAUT; ALEJANDRO COLMAN-LERNER; SILVINA PONCE DAWSON
Optical techniques provide information on various effective diffusion coefficients in the presence of traps
PHYSICAL REVIEW E; Año: 2010 p. 519121 – 5191211
ARIEL CHERNOMORETZ; ALAN BUSH; RICHARD YU; ANDREW GORDON; ALEJANDRO COLMAN-LERNER
Using Cell-ID-1.4 with R for microscope-based cytometry
Current protocols in molecular biology; Año: 2008 vol. 14 p. 1 – 27
RICHARD YU; ORNA RESNEKOV; PIA ABOLA; STEVE ANDREWS; KIRSTEN BENJAMIN; JEHOSHUA BRUCK; IAN BURBULIS; ALEJANDRO COLMAN-LERNER; DREW ENDY; ANDREW GORDON; MARK HALL; LARRY LOK; ROBERT MAXWELL; GUSTAVO PESCE; EDUARD SERRA; RICHARD SMITH; TY THOMSON; ANNIE TSONG; ROGER BRENT
The Alpha Project, a model system for systems biology research
IET Systems Biology; Lugar: London, UK; Año: 2008 vol. 2 p. 222 – 233
RICHARD YU; GUSTAVO PESCE; ALEJANDRO COLMAN-LERNER; LARRY LOK; DAVID PINCUS; EDUARD SERRA; MARK HALL; KIRSTEN BENJAMIN; ANDREW GORDON; ROGER BRENT
Negative feedback that improves information transmission in yeast signalling
NATURE; Año: 2008 vol. 456 p. 755 – 761
ANDREW GORDON (CO-PRIMER AUTOR); ALEJANDRO COLMAN-LERNER (CO-PRIMER AUTOR); TINA CHIN; KIRSTEN BENJAMIN; RICHARD YU; ROGER BRENT
Single-cell quantification of molecules and rates using open-source microscope-based cytometry
Nature Methods; Lugar: New York, New York, USA; Año: 2007 vol. 4 p. 175 – 181
MONICA FAZZINI; GRISELDA VALLEJO; ALEJANDRO COLMAN-LERNER; ROMINA TRIGO; STELLA CAMPO; J LINO BARAÑAO; PATRICIA SARAGÜETA
Transforming growth factor beta1 regulates follistatin mRNA expression during in vitro bovine granulosa cell differentiation
JOURNAL OF CELLULAR PHYSIOLOGY; Lugar: Hoboken, New Jersey, USA; Año: 2006 vol. 207 p. 40 – 48
ALEJANDRO COLMAN-LERNER (CORRESPONDING AUTHOR); ANDREW GORDON; EDUARD SERRA; TINA CHIN; ORNA RESNEKOV; DREW ENDY; GUSTAVO PESCE; ROGER BRENT
Regulated cell-to-cell variation in a cell-fate decision system
NATURE; Lugar: Londres, Reino Unido; Año: 2005 vol. 437 p. 699 – 706
VIRGINIA NOVARO; C PUSTOVRH; ALEJANDRO COLMAN-LERNER; DEREK RADISKY; FABIANA LO NOSTRO; DANTE PAZ; ALICIA JAWERBAUM; ELIDA GONZÁLEZ
Nitric oxide induces gelatinase A (matrix metalloproteinase 2) during rat embryo implantation
FERTILITY AND STERILITY; Año: 2002 vol. 78 p. 1278 – 1287
EUGENIA CHIAPPE; M. L. LATTANZI; ALEJANDRO COLMAN-LERNER; J LINO BARAÑAO; PATRICIA SARAGÜETA
Expression of 3 beta-hydroxysteroid dehydrogenase in early bovine embryo development
MOLECULAR REPRODUCTION AND DEVELOPMENT; Año: 2002 vol. 61 p. 135 – 141
ALEJANDRO COLMAN-LERNER (CORRESPONDING AUTHOR); TINA CHIN; ROGER BRENT
Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.
Cell; Año: 2001 vol. 107 p. 739 – 750
VIRGINIA NOVARO; ALEJANDRO COLMAN-LERNER; F. V. ORTEGA; ALICIA JAWERBAUM; DANTE PAZ; FABIANA LO NOSTRO; C PUSTOVRH; MARTA GIMENO; ELIDA GONZÁLEZ
Regulation of metalloproteinases by nitric oxide in human trophoblast cells in culture
REPRODUCTION FERTILITY AND DEVELOPMENT; Año: 2001 vol. 13 p. 411 – 420
ALEJANDRO COLMAN-LERNER; ROGER BRENT
Using peptide aptamers to analyze the proteome
New Technologies for Life Sciences – A Trends Guide; Año: 2000 vol. supp p. 50 – 56
P POMATA; ALEJANDRO COLMAN-LERNER; J LINO BARAÑAO; MARÍA LAURA FISZMAN
In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta
DEVELOPMENTAL BRAIN RESEARCH; Año: 2000 vol. 120 p. 83 – 86
CR GEYER; ALEJANDRO COLMAN-LERNER (CORRESPONDING AUTHOR); ROGER BRENT
“Mutagenesis” by peptide aptamers identifies genetic network members and pathway connections.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1999 vol. 96 p. 8567 – 8572
ALEJANDRO COLMAN-LERNER; MARIA LAURA FISCHMAN; GUILLERMO LANUZA; MONTGOMERY BISSELL; ALBERTO KORNBLIHTT; J LINO BARAÑAO
Evidence for a role of the alternatively spliced ED-I sequence of fibronectin during ovarian follicular development.
ENDOCRINOLOGY; Año: 1999 vol. 140 p. 2541 – 2548
LEONARDO PIGNATARO; ALEJANDRO COLMAN-LERNER; J LINO BARAÑAO; SARA FISZER DE PLAZAS
Biosynthesis of progesterone derived neurosteroids by developing avian CNS: in vitro effects on the GABAA receptor complex
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE; Año: 1998 vol. 16 p. 433 – 441
ALEJANDRO COLMAN-LERNER; MARIA LAURA FISCHMAN; GUILLERMO LANUZA; PAULA CRAMER; ALBERTO KORNBLIHTT; J LINO BARAÑAO
[Role of different forms of fibronectin in in vitro bovine follicular development]
MEDICINA (BUENOS AIRES); Año: 1997 vol. 57 p. 332 – 336
ALEJANDRO COLMAN-LERNER; DANIEL SALAMONE; EUGENIA CHIAPPE; J LINO BARAÑAO
Comparative studies between freshly isolated and spontaneously immortalized bovine granulosa cells: protein secretion, steroid metabolism, and responsiveness to growth factors
JOURNAL OF CELLULAR PHYSIOLOGY; Año: 1995 vol. 164 p. 395 – 403
Congresos y reuniones científicas
ALEJANDRO COLMAN LERNER; ALAN BUSH; GUSTAVO VASEN
Robustness and information processing in a signal transduction pathway
Molecular Biosystems 2017
Lugar: Puerto Varas; Año: 2017;
ALEJANDRO COLMAN LERNER; ALAN BUSH; GUSTAVO VASEN
Robustness and information processing in a signal transduction pathway
Winter Q-bio 2017
Año: 2017;
ALEJANDRO COLMAN LERNER; ALEJANDRA VENTURA; ALAN BUSH; GUSTAVO VASEN
Use of information far from steady-state by signal transduction systems.
Q-Bio 2015
Lugar: Blacksburg, Virginia; Año: 2015;
PAULA DUNAYEVICH; RODRIGO BALTANÁS; ALEJANDRO COLMAN LERNER
Cross-talk between ERK and p38-based MAPK pathways in the yeast S. cerevisiae.
SAIB Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVII Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular (BUENOS AIRES)
Lugar: Buenos Aires; Año: 2013;
VICTORIA REPETTO; ALAN BUSH; MATTHEW WINTERS; PETER PRYCIAK; ALEJANDRO COLMAN LERNER
Single cell analysis of membrane recruitment dynamics of the mating MAPK pathway scaffold protein
CELL BIOLOGY OF YEASTS
Lugar: Cold Spring Harbor; Año: 2013;
EDGAR ALTSZYLER; ALEJANDRA VENTURA; ALEJANDRO COLMAN LERNER; ARIEL CHERNOMORETZ
Constrains on a module?s effective sensitivity by the input and readout dynamic range
The Seventh q-bio Conference
Lugar: Santa Fe; Año: 2013;
MATÍAS BLAUSTEIN; DANIELA PÉREZ-MUNIZAGA; MANUEL ALEJANDRO SÁNCHEZ; CAROLINA URRUTIA; ALICIA GRANDE; GUILLERMO RISSO; ANABELLA SREBROW; SEBASTIAN BERNALES; JENNIFER ALFARO; ALEJANDRO COLMAN LERNER
Signaling AKTivation and UPRegulation dynamics control opposing cell fate choices
International Conference on Systems Biology
Lugar: Toronto; Año: 2012;
ALAN BUSH; ALEJANDRO COLMAN LERNER
Quantitative Measure of Scaffold Protein Membrane Recruitment in Live Cells
International Conference on Systems Biology
Lugar: Toronto; Año: 2012;
VICTORIA REPETTO; ALAN BUSH; MATTHEW WINTERS; PETER PRYCIAK; ALEJANDRO COLMAN LERNER
Hidden behind the mean: single cell analysis of the membrane recruitment dynamics of yeast mating MAPK pathway scaffold protein
The Second South American Symposium on Signal Transduction and Translational Medicine
Lugar: Los Cocos; Año: 2012;
ALICIA GRANDE; EDGAR ALTSZYLER; ARIEL CHERNOMORETZ; ALEJANDRO COLMAN LERNER
Interaction between the Cell Cycle and a Cell Fate Decision System in Yeast Saccharomyces cerevisiae: a Systems Biology Approach
The Second South American Symposium on Signal Transduction and Translational Medicine
Lugar: Los Cocos; Año: 2012;
ALEJANDRO COLMAN LERNER; ALAN BUSH; ALEJANDRA VENTURA; ARIEL CHERNOMORETZ
INFORMATION TRANSMISSION AND GRADIENT SENSING IN THE Saccharomyces cerevisiae PHEROMONERESPONSE PATHWAY
SAIB 47th Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVII Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Potrero de los Funes; Año: 2011;
ALEJANDRO COLMAN LERNER; ALEJANDRA VENTURA; ALAN BUSH; ARIEL CHERNOMORETZ
Gradient sensing in the S.cerevisiae pheromone response pathway
Yeast Systems Biology Course – Symposium
Lugar: Punta del Este; Año: 2011;
MATÍAS BLAUSTEIN; ALFARO J; PÉREZ D; URRUTIA C; SÁNCHEZ MANUEL; ALICIA GRANDE; GUILLERMO RISSO; BURKINSHAW B; FEDEDA JP; SREBROW ANABELLA; BERNALES S; ALEJANDRO COLMAN LERNER
Akt ALLOWS CYTOSOLIC REGULATION OF
SAIB 47th Annual Meeting Argentine Society of Biochemistry and Molecular Biology XLVII Reunión Anual Argentina de Investigación en Bioquimica y Biología Molecular
Lugar: Potrero de Funes; Año: 2011;
VICTORIA REPETTO; ALAN BUSH; ALEJANDRO COLMAN LERNER
ANALYSIS OF SCAFFOLD-PROTEIN MEMBRANE RECRUITMENT DYNAMICS DURING PHEROMONE RESPONSE IN Saccharomycfes cerevisiae
SAIB 47th Annual Meeting Argentine Society of Biochemistry and Molecular Biology XLVII Reunión Anual Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Potrero de Funes; Año: 2011;
ALICIA GRANDE; ALTSZYLER E; BALENZUELA P; BRUNO L; LAJE R; ARIEL CHERNOMORETZ; ALEJANDRO COLMAN LERNER
STUDYING THE CELL CYCLE AND PHEROMONE RESPONSE PATHWAY INTERACTION IN YEAST Saccharomycfes cerevisiae
SAIB 47th Annual Meeting Argentine Society of Biochemistry and Molecular Biology XLVII Reunión Anual Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Potrero de Funes; Año: 2011;
ALEJANDRO COLMAN LERNER
Signal anticipation in a GPCR pathwaySingle cell measurements of scaffold recruitment
International Society of Computational Biology-Latin America
Lugar: Montevideo, Uruguay; Año: 2010;
LUCÍA DURRIEU; GUNNAR CEDERSUND; ALAN BUSH; ALEJANDRO COLMAN-LERNER
Quantitative study of mother-daughter asymmetry in Ace2 localization in yeast
International society for computational biology-latin america
Lugar: Montevideo, Uruguay; Año: 2010;
LUCIANA BRUNO; PABLO BALENZUELA; ARIEL CHERNOMORETZ; RODRIGO LAJE; ELIZABETH KENNEDY; ALEJANDRO COLMAN-LERNER
Cell-fate decisions in mating pheromone stimulated yeast. A systems biology study
International society for computational biology-latin america
Lugar: Montevideo, Uruguay; Año: 2010;
ALAN BUSH; ARIEL CHERNOMORETZ; ALEJANDRO COLMAN-LERNER
Dose response alignment in a G protein coupled receptor pathway
International Society of Computational Biology-Latin America
Lugar: Montevideo, Uruguay; Año: 2010;
LUCIA DURRIEU; MUNZER U; ALAN BUSH; GUNNAR CEDERSUND; ALEJANDRO COLMAN LERNER
QUANTITATIVE STUDY OF MOTHER-DAUGHTER ASYMMETRY IN Ace2 LOCALIZATION IN YEAST
46th Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVI Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Puerto Madryn – Chubut ; Año: 2010;
GUILLERMO RISSO; FEDERICO PELISCH; BERTA POZZI; MATIAS BLAUSTEIN; ALEJANDRO COLMAN LERNER; ANABELLA SREBROW
REGULATION OF Akt ACTIVITY BY SUMO CONJUGATION
SAIB 46th Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVI Reunión Anual Sociedad Argentina en Bioquímica y Biología Molecular.
Lugar: Puerto Madryn – Chubut; Año: 2010;
ALAN BUSH; CHERNOMORETZ A; ALEJANDRO COLMAN LERNER
MEASUREMENT OF EFFECTIVE SCAFFOLD PROTEIN AFFINITY TO MEMBRANE BINDING SITES BY IN VIVO SCATCHARD
SAIB 46th Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVI Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular.
Lugar: Puerto Madryn – Chubut; Año: 2010;
ALICIA GRANDE; KENNEDY E; RODRIGO BALTANÁS; ALEJANDRO COLMAN LERNER
ENERGY ME TABOL I SM MODULAT E S THE PHEROMONE RESPONSE GPCR PATHWAY IN THE YEAST S.cerevisiae
SAIB 46th Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVI Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Argentina; Año: 2010;
MATÍAS BLAUSTEIN; ALFARO J; URRUTIA C; SANCHEZ MANUEL; ALICIA GRANDE; BURKINSHAW B; BERNALES S; ALEJANDRO COLMAN LERNER
Akt ACTIVITY REGULATES THE UNFOLDED PROTEIN RESPONSE IN CULTURED MAMMALIAN CELLS
SAIB 46th Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVI Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Puerto Madryn – Chubut; Año: 2010;
RODRIGO BALTANÁS; STEFAN HOHMANN; ALEJANDRO COLMAN LERNER
INTEGRATING SIGNALS: ENVIROMENT LINKS MAPK PATHWAYS IN S. cerevisiae
SAIB 46th Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVI Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Puerto Madryn – Chubut; Año: 2010;
ALEJANDRA VENTURA; MATIAS GOLDÍN; ALAN BUSH; CHERNOMORETZ A; ALEJANDRO COLMAN LERNER
DYNAMICS OF GRADIENT SENSING IN SINGLE CELLS
SAIB 46th Annual Meeting Argentine Society for Biochemistry and Molecular Biology XLVI Reunión Anual Sociedad Argentina de Investigación en Bioquímica y Biología Molecular
Lugar: Puerto Madryn – Chubut ; Año: 2010;
ALEJANDRO COLMAN LERNER
Single cell analyses of fate decisions in yeast
ADVANCES IN STEM CELL RESEARCH: Stem cells, systems & synthetic biology
Lugar: Homerton College, Cambridge, UK; Año: 2009;
ALEJANDRO COLMAN LERNER
Dynamics of the activation of the pheromone response pathway
MAP Kinase-based signal transduction in yeast and mammalian cells
Lugar: Kiental, Suiza; Año: 2009;
LUCÍA DURRIEU; GUNNAR CEDERSUND; ALEJANDRO COLMAN-LERNER
Quantitative study of Ace2 mother‐daughter asymmetry
Exciting Biologies: Biology in Balance
Lugar: Hetel Sofitel, Campana, Pcia BsAs, Argentina; Año: 2009;
ALAN BUSH; ALEJANDRO COLMAN-LERNER
Quantitative measurement of scaffold recruitment to the plasma membrane by confocal microscopy
MAP Kinase-based signal transduction in yeast and mammalian cells
Lugar: Kiental, Suiza; Año: 2009;
MATÍAS BLAUSTEIN; ALICIA GRANDE; ALEJANDRO COLMAN-LERNER
Analysis of signaling pathways dynamics in animal single cells
Exciting Biologies: Biology in Balance
Lugar: Hetel Sofitel, Campana, Pcia BsAs, Argentina; Año: 2009;
RODRIGO BALTANÁS; DAVID LEVIN; STEFAN HOHMANN; ALEJANDRO COLMAN-LERNER
COORDINATED ACTIVATION OF THE MAPK NETWORK BY MATING PHEROMONE
Yeast Cell Biology Meeting
Lugar: Cold Spring Harbor Laboratory, New York, USA; Año: 2009;
ARIEL CHERNOMORETZ; ALAN BUSH; PABLO BALENZUELA; LUCIANA BRUNO; RODRIGO LAJE; TY THOMSON; ROGER BRENT; ALEJANDRO COLMAN LERNER
Signal anticipation in a GPCR pathway — Single cell measurements of scaffold recritment show rapid dose response alignement before receptor binding reaches equilibrium
Computational Cell Biology Meeting
Lugar: Hinxton, Reino Unido; Año: 2008;
LUCÍA DURRIEU; ALAN BUSH; ALEJANDRO COLMAN-LERNER
THE NUCLEAR ENVELOPE DIFFUSION BARRIER IS REQUIRED FOR CORRECT MOTHER-DAUGHTER ASYMMETRY IN YEAST
XLIV Reunión Anual SAIB
Lugar: Villa Carlos Paz, Córdoba, Argentina; Año: 2008;
RODRIGO BALTANÁS; ALEJANDRO COLMAN-LERNER
Activation of mating response converts the HOG pathway from a transient to a sustained response
Ninth International Conference on Systems Biology
Lugar: Gotemburgo, Suecia; Año: 2008;
ARIEL CHERNOMORETZ; ALAN BUSH; PABLO BALENZUELA; LUCIANA BRUNO; RODRIGO LAJE; TY THOMSON; ROGER BRENT; ALEJANDRO COLMAN LERNER
“Signal anticipation in a GPCR pathwaySingle cell measurements of scaffold recruitment show rapid does response alignment before receptor binding reaches equilibrium
Systems biology of MAP kinase pathways in S.cereveisiae and in mammalian cells
Lugar: Okinawa Institute of Science and Technology, Okinawa, Japón; Año: 2008;
ALEJANDRO COLMAN LERNER; ANDREW GORDON; GUSTAVO PESCE; ROGER BRENT
The variable cell, signal transduction at the single cell level
Systems biology of MAP kinase pathways in S.cereveisiae and in mammalian cells
Lugar: Okinawa Institute of Science and Technology, Okinawa, Japón; Año: 2008;
ALEJANDRO COLMAN LERNER; TY THOMSON; ANDREW GORDON; ALAN BUSH; PABLO BALENZUELA; RODRIGO LAJE; LUCIANA BRUNO; ARIEL CHERNOMORETZ; KIRSTEN BENJAMIN; ROGER BRENT
Single-cell imaging of membrane recruitment of signaling scaffold: fractional receptor occupancy is sensed quantitatively seconds after addition of ligand.
The Eigth International Conference on Systems Biology
Lugar: Long Beach, California, Estados Unidos; Año: 2007;
JUAN PABLO FEDEDA; ALEJANDRO COLMAN-LERNER; ALBERTO KORNBLIHTT
Single cell alternative splicing
Gene Expression and RNA Processing
Lugar: Bariloche, Pcia de Río Negro; Año: 2007;
JUAN PABLO FEDEDA; ALEJANDRO COLMAN-LERNER; ALBERTO KORNBLIHTT
Single cell alternative splicing
Cell Biology, Signaling and Alternative Splicing
Lugar: Bariloche, Pcia de Río Negro; Año: 2007;
ALEJANDRO COLMAN LERNER; RICHARD YU; ANDREW GORDON; TINA CHIN; GUSTAVO PESCE; ROGER BRENT
“Sources and control of cell to cell variation in the response of yeast to mating pheromone”.
The Seventh International Conference on Systems Biology
Lugar: Yokohama, Japón.; Año: 2006;
ALEJANDRO COLMAN LERNER; RICHARD YU; ANDREW GORDON; GUSTAVO PESCE; ROGER BRENT
Single cell measurements, physiology and cell to cell variation during the activation of the S.cerevisiae pheromone response pathway.
Cell Signalling Systems Biology
Lugar: Rostock-Warnemunde, Alemania; Año: 2006;
ALEJANDRO COLMAN LERNER; ANDREW GORDON; EDUARD SERRA; TINA CHIN; ORNA RESNEKOV; DREW ENDY; GUSTAVO PESCE; ROGER BRENT
Regulated Cell to Cell Variation in a Cell Fate Decision System
The Sixth International Conference on Systems Biology
Lugar: Boston, Massachusetts, Estados Unidos; Año: 2005;