CV
Dr. Daniel Tomsic
Profesor, Departamento de Fisiología, Biología Molecular y Celular, FCEN, UBA.
Investigador Principal CONICET
Datos académicos
Artículos
DI-BELLA, JUAN PABLO; COLMAN-LERNER, ALEJANDRO; VENTURA, ALEJANDRA C.
Properties of cell signaling pathways and gene expression systems operating far from steady-state
Scientific Reports; Año: 2018 vol. 8
VICTORIA REPETTO; MATTHEW WINTERS; ALAN BUSH; WOLFGANG REITER; DAVID MARIA HOLLENSTEIN; GUSTAV AMMERER; PETER PRYCIAK; ALEJANDRO COLMAN LERNER
CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5
MOLECULAR CELL; Lugar: United States; Año: 2018 vol. 69
GUSTAVO PESCE; STEFAN ZDRALJEVIC; WILLIAM PERIA; ALAN BUSH; VICTORIA REPETTO; DAN ROCKWELL; RICHARD YU; ALEJANDRO COLMAN LERNER; ROGER BRENT
Single-cell profiling screen identifies microtubule-dependent reduction of variability in cell signaling
MOLECULAR SYSTEMS BIOLOGY; Lugar: Londres; Año: 2018 vol. 14 p. 1 – 20
PAULA DUNAYEVICH; RODRIGO BALTANÁS; JOSÉ CLEMENTE; ALICIA COUTO; DAIANA SAPOCHNIK; GUSTAVO VASEN; ALEJANDRO COLMAN LERNER
Heat-stress triggers MAPK crosstalk to turn on the hyper-osmotic response pathway
Scientific Reports; Año: 2018
EDGAR ALTSZYLER; ALEJANDRA VENTURA; ALEJANDRO COLMAN-LERNER; ARIEL CHERNOMORETZ
Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations
PLOS ONE; Lugar: San Francisco; Año: 2017
STEVE ANDREWS; WILLIAM PERIA; RICHARD YU; ALEJANDRO COLMAN LERNER; ROGER BRENT
Push-pull and feedback mechanisms can align signaling system outputs with inputs
Cell Systems; Año: 2016 vol. 3 p. 1 – 12
ALAN BUSH; GUSTAVO VASEN; ANDREAS CONSTANTINOU; PAULA DUNAYEVICH; INÉS PATOP; MATÍAS BLAUSTEIN; ALEJANDRO COLMAN LERNER
Yeast GPCR signaling reflects the fraction of occupied receptors, not the number
MOLECULAR SYSTEMS BIOLOGY; Lugar: Heidelberg; Año: 2016 vol. 12 p. 1 – 20
ANDREAS DONCIC; OGUZHAN ATAY; ERVIN VALK; ALICIA GRANDE; ALAN BUSH; GUSTAVO VASEN; ALEJANDRO COLMAN LERNER; MART LOOG; JAN SKOTHEIM
Compartmentalization of a bistable switch enables memory to cross a feedback-driven transition
CELL; Lugar: United States; Año: 2015 vol. 120
MARCUS KARLSSON; DAVID JANSEN; LUCÍA DURRIEU; ALEJANDRO COLMAN LERNER; MARIA KJELLSSON; GUNNAR CEDERSUND
Nonlinear mixed-effects modelling for single cell estimation: when, why, and how to use it
BMC SYSTEMS BIOLOGY; Lugar: Londres; Año: 2015 vol. 9 p. 1 – 15
EDGAR ALTSZYLER; ALEJANDRA VENTURA; ALEJANDRO COLMAN LERNER; ARIEL CHERNOMORETZ
Impact of upstream and downstream constraints on a signaling module’s ultrasensitivity
PHYSICAL BIOLOGY; Lugar: Londres; Año: 2014 vol. 11
LORENA SIGAUT; JOHN PEARSON; ALEJANDRO COLMAN LERNER; SILVINA PONCE DAWSON
Messages Do Diffuse Faster Than Messengers: Reconciling disparate estimates of the morphogen Bicoid diffusion coefficient
PLOS COMPUTATIONAL BIOLOGY; Lugar: San Francisco; Año: 2014 p. 1 – 15
ALEJANDRA VENTURA; ALAN BUSH; GUSTAVO VASEN; MATÍAS GOLDÍN; BRIANNE BURKINSHAW; NIRVEEK BHATTACHARJEE; ALBERT FOLCH; ROGER BRENT; ARIEL CHERNOMORETZ; ALEJANDRO COLMAN LERNER
Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2014
ALAN BUSH; ALEJANDRO COLMAN LERNER
Quantitative Measurement of Protein Relocalization in Live Cells
BIOPHYSICAL JOURNAL; Lugar: United States; Año: 2013 vol. 104 p. 727 – 736
RODRIGO BALTANÁS; ALAN BUSH; ALICIA COUTO ; LUCIA DURRIEU; STEFAN HOHMANN; ALEJANDRO COLMAN LERNER
Pheromone-Induced Morphogenesis Improves Osmoadaptation Capacity by Activating the HOG MAPK Pathway
SCIENCE SIGNALING; Año: 2013 vol. 6 p. 1 – 14
MATÍAS BLAUSTEIN; DANIELA PÉREZ-MUNIZAGA; MANUEL ALEJANDRO SÁNCHEZ; CAROLINA URRUTIA; ALICIA GRANDE; GUILLERMO RISSO; ANABELLA SREBROW; JENNIFER ALFARO; ALEJANDRO COLMAN LERNER
Modulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxia
PLOS ONE; Lugar: San Francisco; Año: 2013 p. 1 – 14
GUILLERMO RISSO; FEDERICO PELISCH; BERTA POZZI; PABLO MAMMI; MATÍAS BLAUSTEIN; ALEJANDRO COLMAN LERNER; ANABELLA SREBROW
Modification of Akt by SUMO conjugation regulates alternative splicing and cell cycle
CELL CYCLE; Lugar: Austin, Texas; Año: 2013 vol. 12 p. 1 – 12
ALAN BUSH; ARIEL CHERNOMORETZ; RICHARD YU; ANDREW GORDON; ALEJANDRO COLMAN LERNER
Using Cell-ID 1.4 with R for Microscope-Based Cytometry
Current Protocols in Molecular Biology; Año: 2012 p. 1 – 26
JÖRG SCHABER; RODRIGO BALTANÁS; ALAN BUSH; EDDA KLIPP; ALEJANDRO COLMAN LERNER
Modelling reveals novel roles of two parallel signalling pathways and homeostatic feedbacks in yeast
MOLECULAR SYSTEMS BIOLOGY; Lugar: Londres; Año: 2012 p. 1 – 17
MARIANA RIGGIO; MARÍA LAURA POLO; MATÍAS BLAUSTEIN; ALEJANDRO COLMAN LERNER; ISABEL LÜTHY; CLAUDIA LANARI; VIRGINIA NOVARO
PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer
CARCINOGENESIS; Lugar: Oxford; Año: 2011 p. 1 – 10
TY THOMSON; KIRSTEN BENJAMIN; ALAN BUSH; TONYA LOVE; DAVID PINCUS; ORNA RESNEKOV; RICHARD YU; ANDREW GORDON; ALEJANDRO COLMAN LERNER; DREW ENDY; ROGER BRENT
Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2011
BERND BODENMILLER; STEFANIE WANKA; CLAUDINE KRAFT; JÖRG URBAN; DAVID CAMPBELL; PATRICK PEDRIOLI; BERTRAN GERRITS; PAOLA PICOTTI; HENRY LAM; OLGA VITEK; MI-YOUN BRUSNIAK; BERND ROSCHITZKI; CHAO ZHANG; RALPH SCHLAPBACH; KEVAN SHOKAT; ALEJANDRO COLMAN-LERNER; ALEXEY I. NESVIZHSKII; MATTHIAS PETER; ROBBIE LOEWITH; CHRISTIAN VON MERING; RUEDI AEBERSOLD
Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations of Kinases and Phosphatases in Yeast
SCIENCE SIGNALING; Año: 2010
LORENA SIGAUT; ALEJANDRO COLMAN-LERNER; SILVINA PONCE DAWSON
Optical techniques provide information on various effective diffusion coefficients in the presence of traps
PHYSICAL REVIEW E; Año: 2010 p. 519121 – 5191211
ARIEL CHERNOMORETZ; ALAN BUSH; RICHARD YU; ANDREW GORDON; ALEJANDRO COLMAN-LERNER
Using Cell-ID-1.4 with R for microscope-based cytometry
Current protocols in molecular biology; Año: 2008 vol. 14 p. 1 – 27
RICHARD YU; ORNA RESNEKOV; PIA ABOLA; STEVE ANDREWS; KIRSTEN BENJAMIN; JEHOSHUA BRUCK; IAN BURBULIS; ALEJANDRO COLMAN-LERNER; DREW ENDY; ANDREW GORDON; MARK HALL; LARRY LOK; ROBERT MAXWELL; GUSTAVO PESCE; EDUARD SERRA; RICHARD SMITH; TY THOMSON; ANNIE TSONG; ROGER BRENT
The Alpha Project, a model system for systems biology research
IET Systems Biology; Lugar: London, UK; Año: 2008 vol. 2 p. 222 – 233
RICHARD YU; GUSTAVO PESCE; ALEJANDRO COLMAN-LERNER; LARRY LOK; DAVID PINCUS; EDUARD SERRA; MARK HALL; KIRSTEN BENJAMIN; ANDREW GORDON; ROGER BRENT
Negative feedback that improves information transmission in yeast signalling
NATURE; Año: 2008 vol. 456 p. 755 – 761
ANDREW GORDON (CO-PRIMER AUTOR); ALEJANDRO COLMAN-LERNER (CO-PRIMER AUTOR); TINA CHIN; KIRSTEN BENJAMIN; RICHARD YU; ROGER BRENT
Single-cell quantification of molecules and rates using open-source microscope-based cytometry
Nature Methods; Lugar: New York, New York, USA; Año: 2007 vol. 4 p. 175 – 181
MONICA FAZZINI; GRISELDA VALLEJO; ALEJANDRO COLMAN-LERNER; ROMINA TRIGO; STELLA CAMPO; J LINO BARAÑAO; PATRICIA SARAGÜETA
Transforming growth factor beta1 regulates follistatin mRNA expression during in vitro bovine granulosa cell differentiation
JOURNAL OF CELLULAR PHYSIOLOGY; Lugar: Hoboken, New Jersey, USA; Año: 2006 vol. 207 p. 40 – 48
ALEJANDRO COLMAN-LERNER (CORRESPONDING AUTHOR); ANDREW GORDON; EDUARD SERRA; TINA CHIN; ORNA RESNEKOV; DREW ENDY; GUSTAVO PESCE; ROGER BRENT
Regulated cell-to-cell variation in a cell-fate decision system
NATURE; Lugar: Londres, Reino Unido; Año: 2005 vol. 437 p. 699 – 706
VIRGINIA NOVARO; C PUSTOVRH; ALEJANDRO COLMAN-LERNER; DEREK RADISKY; FABIANA LO NOSTRO; DANTE PAZ; ALICIA JAWERBAUM; ELIDA GONZÁLEZ
Nitric oxide induces gelatinase A (matrix metalloproteinase 2) during rat embryo implantation
FERTILITY AND STERILITY; Año: 2002 vol. 78 p. 1278 – 1287
EUGENIA CHIAPPE; M. L. LATTANZI; ALEJANDRO COLMAN-LERNER; J LINO BARAÑAO; PATRICIA SARAGÜETA
Expression of 3 beta-hydroxysteroid dehydrogenase in early bovine embryo development
MOLECULAR REPRODUCTION AND DEVELOPMENT; Año: 2002 vol. 61 p. 135 – 141
ALEJANDRO COLMAN-LERNER (CORRESPONDING AUTHOR); TINA CHIN; ROGER BRENT
Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.
Cell; Año: 2001 vol. 107 p. 739 – 750
VIRGINIA NOVARO; ALEJANDRO COLMAN-LERNER; F. V. ORTEGA; ALICIA JAWERBAUM; DANTE PAZ; FABIANA LO NOSTRO; C PUSTOVRH; MARTA GIMENO; ELIDA GONZÁLEZ
Regulation of metalloproteinases by nitric oxide in human trophoblast cells in culture
REPRODUCTION FERTILITY AND DEVELOPMENT; Año: 2001 vol. 13 p. 411 – 420
ALEJANDRO COLMAN-LERNER; ROGER BRENT
Using peptide aptamers to analyze the proteome
New Technologies for Life Sciences – A Trends Guide; Año: 2000 vol. supp p. 50 – 56
P POMATA; ALEJANDRO COLMAN-LERNER; J LINO BARAÑAO; MARÍA LAURA FISZMAN
In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta
DEVELOPMENTAL BRAIN RESEARCH; Año: 2000 vol. 120 p. 83 – 86
CR GEYER; ALEJANDRO COLMAN-LERNER (CORRESPONDING AUTHOR); ROGER BRENT
“Mutagenesis” by peptide aptamers identifies genetic network members and pathway connections.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1999 vol. 96 p. 8567 – 8572
ALEJANDRO COLMAN-LERNER; MARIA LAURA FISCHMAN; GUILLERMO LANUZA; MONTGOMERY BISSELL; ALBERTO KORNBLIHTT; J LINO BARAÑAO
Evidence for a role of the alternatively spliced ED-I sequence of fibronectin during ovarian follicular development.
ENDOCRINOLOGY; Año: 1999 vol. 140 p. 2541 – 2548
LEONARDO PIGNATARO; ALEJANDRO COLMAN-LERNER; J LINO BARAÑAO; SARA FISZER DE PLAZAS
Biosynthesis of progesterone derived neurosteroids by developing avian CNS: in vitro effects on the GABAA receptor complex
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE; Año: 1998 vol. 16 p. 433 – 441
ALEJANDRO COLMAN-LERNER; MARIA LAURA FISCHMAN; GUILLERMO LANUZA; PAULA CRAMER; ALBERTO KORNBLIHTT; J LINO BARAÑAO
[Role of different forms of fibronectin in in vitro bovine follicular development]
MEDICINA (BUENOS AIRES); Año: 1997 vol. 57 p. 332 – 336
ALEJANDRO COLMAN-LERNER; DANIEL SALAMONE; EUGENIA CHIAPPE; J LINO BARAÑAO
Comparative studies between freshly isolated and spontaneously immortalized bovine granulosa cells: protein secretion, steroid metabolism, and responsiveness to growth factors
JOURNAL OF CELLULAR PHYSIOLOGY; Año: 1995 vol. 164 p. 395 – 403
Congresos y reuniones científicas